What does this research mean for the field?

Among female patients with acne, an increased LH/FSH ratio is the most prominent hormonal disturbance distinguishing those with Polycystic Ovary Syndrome (PCOS) from those without, whereas testosterone and DHEAS levels do not significantly differ. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To compare the hormonal and radiological profiles of acne patients presenting with and without polycystic ovary syndrome (PCOS).

September 2, 2026Advances in Clinical Medical ResearchOpen Access

Hormonal and Radiological Profile of Acne Patients With Polycystic Ovary Syndrome (Pcos)

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Authors

ATAmit K Tiwari PAPuneet Agarwal NANaushin Aara

Discussion

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Implication

Cross-sectional study finds an elevated LH to FSH ratio in acne patients with PCOS, indicating gonadotropin imbalance as a primary disturbance.

Key Points

To compare the hormonal and radiological profiles of acne patients presenting with and without polycystic ovary syndrome (PCOS).
Conducted a hospital-based cross-sectional observational study in 150 patients presenting with acne evaluated for underlying PCOS.
Assessed serum testosterone, dehydroepiandrosterone (DHEAS), LH, FSH, insulin, prolactin, and pelvic ultrasound imaging in both PCOS and non-PCOS cohorts.
PCOS was diagnosed in 44% (66/150) of acne patients, with pelvic ultrasonography revealing ovarian cysts in 30.66% (46/150).
An LH:FSH ratio ≥ 2 occurred in 32 patients, representing 93.75% of the PCOS group compared to 6.25% of the non-PCOS group (p = 0.0000).
Differences between the PCOS and non-PCOS groups were not statistically significant for testosterone (53.68 ± 30.87 vs 47.28 ± 61.13 ng/dl), DHEAS (215.65 ± 115.22 vs 170.76 ± 63.94 μg/dl), prolactin (13.01 ± 9.64 vs 14.69 ± 7.71 ng/ml), or insulin (6.2 ± 4.73 vs 6.73 ± 6.09 μIU/ml) (all p > 0.05).

Cite This Study

Tiwari et al. (2026) studied this question.

synapsesocial.com/papers/6a97e305c562ede874ec78c7 https://doi.org/10.5281/zenodo.22194499

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Implication

Cross-sectional study finds an elevated LH to FSH ratio in acne patients with PCOS, indicating gonadotropin imbalance as a primary disturbance.

Hormonal and Radiological Profile of Acne Patients With Polycystic Ovary Syndrome (Pcos)

Discussion

Member takes

Implication

Key Points

Cite This Study

Hormonal and Radiological Profile of Acne Patients With Polycystic Ovary Syndrome (Pcos)

Discussion

Member takes

Implication

Key Points

Cite This Study

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