Clinical review reveals severe multi-organ toxicity and diagnostic hurdles in patients exposed to Ayurvedic botanicals, highlighting the need for stricter standardization and forensic reporting.
Ayurveda, one of the oldest systems of medicine, utilizes a wide range of plant-based formulations for preventive and therapeutic purposes. Despite its widespread acceptance and perception as a “natural and safe” alternative to modern medicine, several Ayurvedic plants possess inherent toxic properties when misused, overdosed, or improperly processed. Increasing globalization, self-medication practices, and over-the-counter availability of herbal preparations have led to a rise in plant-related toxicities presenting in emergency departments. These toxicities range from mild gastrointestinal disturbances to severe organ damage, including hepatotoxicity, nephrotoxicity, cardiotoxicity, and neurotoxicity .From a medicolegal perspective, such cases present unique challenges in diagnosis, documentation, and legal accountability. Issues such as misidentification of plant species, lack of standardization in preparation, contamination with heavy metals, and absence of proper labeling further complicate clinical and forensic evaluation . Hospitals frequently encounter cases where patients fail to disclose herbal intake, leading to delayed diagnosis and adverse outcomes . Additionally, medico-legal implications arise in cases of accidental poisoning, suicidal ingestion, malpractice, and negligence in prescribing or dispensing herbal drugs .This review aims to analyze common Ayurvedic plants known for their toxic potential, outline their clinical manifestations, and highlight the associated medico-legal concerns encountered in hospital settings. Ten commonly implicated plants are discussed in detail, focusing on their toxic principles, mechanisms of toxicity, clinical presentation, and forensic importance .Understanding the dual nature of Ayurvedic plants-as therapeutic agents and potential toxins is crucial for clinicians, forensic experts, and policymakers. Improved awareness, regulation, and integration of traditional and modern medical knowledge are essential to minimize risks and enhance patient safety.
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Haricharan et al. (2026) studied this question.
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