Summary To determine whether selective absorption of immunoglobulin occurs in newborn unanaesthetised calves, the concentrations of IgG1, IgG2, IgM and IgA were measured in thoracic duct lymph shortly after the feeding of colostrum. In the 13 calves studied it was found that the concentrations of IgG1, IgG2, IgM and IgA in lymph expressed as a proportion of the concentration of the same immunoglobulins in the colostrum fed were not significantly different. It is concluded that immunoglobulins in the molecular weight range of 150,000 to 1,000,000 are absorbed non‐selectively in the calf.
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Brandon et al. (1971) studied this question.