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THIS report deals with a new method for the colorimetric determination of arginine exopeptidase activity of human serum, and the values obtained in various diseases, in particular those involving the pancreas.In the past few years there has been a revival of interest in the proteolytic and related enzymes of human serum. Recently, the trypsin and leucine aminopeptidase activity of the serum has been shown to be increased in acute and chronic pancreatitis and in carcinoma of the pancreas.1 2 3 The classification of enzymes that act on proteins or peptides is difficult. The activity of serum on arginine amides and esters . . .
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Michael E. Brown (1959) studied this question.
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