Key result
Parental overweight and hypertension were significantly associated with children's blood pressure, but this association was largely mediated (30.4-92.2%) by the children's own adiposity indices.
Why the study?
The study evaluated the association between parental factors and children's blood pressure status, and the extent to which this association was mediated by children's adiposity indices.
Does parental overweight and hypertension increase children's blood pressure in school-aged children?
Cross-Sectional (n=3,316)
Yes
Does parental overweight and hypertension increase children's blood pressure in school-aged children?
The association between parental overweight or hypertension and children's blood pressure is largely mediated by the children's own adiposity indices, particularly BMI.
Parental overweight and hypertension link to child BP supports family adiposity screening; leaves open causal effects and intervention targets.
BACKGROUND: We evaluated the association between parental factors (overweight, history of hypertension, and education level) and children's blood pressure status. Further, we evaluated to what extent the potential association could be interpreted by children's adiposity indices. METHODS: The current study included 3316 Chinese school students (1579 girls and 1737 boys, aged 6-14 years) and their parents. Parents reported information on their height, body weight, history of hypertension, and the highest education level. Trained medical staff measured children's blood pressure, height, body weight, waist circumference (WC), and percentage of body fat (PBF, assessed by bio-impedance method). Z-score of all three indices were calculated and used in the analysis. We used generalized linear model to evaluate the association between parental information and z-score of children's blood pressure. Meditation analysis was used to evaluate the proportion contributed by z-score of children's adiposity indices (BMI, WC, and PBF). RESULTS: < 0.05 for all). Approximately 30.4-92.2% of the association between these two parental factors and children's systolic blood pressure were mediated by children's adiposity indices, and 22.3-55.6% for children's diastolic blood pressure. The strongest meditative factor, among the three obesity indices, was children's BMI z-score. CONCLUSIONS: The association between parental factors and children's blood pressure was mainly mediated by children's adiposity indices.
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Xu et al. (2019) conducted a cross-sectional in Childhood blood pressure (n=3,316). Parental overweight and hypertension vs. Parents with normal weight and no history of hypertension was evaluated on Children's systolic and diastolic blood pressure z-scores (p=<0.05). Parental overweight and hypertension were significantly associated with children's blood pressure, but this association was largely mediated (30.4-92.2%) by the children's own adiposity indices.
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