Key result
High LDL and high blood pressure were significantly associated with increased carotid intima-media thickness in children on dialysis.
Why the study?
The risk factors for cardiovascular assessment among children on dialysis needed to be investigated.
Are LDL and blood pressure associated with increased carotid intima-media thickness and pulse wave velocity in pediatric patients on dialysis?
Cross-Sectional (n=19)
No
Are LDL and blood pressure associated with increased carotid intima-media thickness and pulse wave velocity in pediatric patients on dialysis?
High LDL is significantly associated with increased carotid intima-media thickness in children on dialysis, suggesting it as a potential target for preventing vasculopathy.
High LDL and BP associated with increased cIMT in pediatric dialysis; leaves open whether targeting them prevents vasculopathy.
INTRODUCTION: We searched for risk factors of cardiovascular assessment among children on dialysis. METHODS: This is a cross-sectional study of cardiovascular assessment of all patients on dialysis at Ege University Children's Hospital. Pediatric patients between the ages of 6 and 21 who were on HD and peritoneal dialysis treatment were included in the study. Cardiovascular evaluation included left ventricular mass index (LVMI), pulse wave velocity (PWV), and carotid intima-media thickness (cIMT) measurements. RESULTS: Nineteen patients were included in this study. The LDL had a correlation with the cIMT z-score, but not to PWVz-score. Binary Logistic regression analysis found that only LDL was significantly associated to increased cIMT. CONCLUSION: This study reports an association between high LDL and high BP increased cIMT on dialyzed children. Strategies to reduce LDL and BP in dialysis patients may prevent vasculopathy and long-term cardiovascular complications.
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Tunçay et al. (2022) conducted a cross-sectional in dialysis (n=19). High LDL and high blood pressure was evaluated on increased carotid intima-media thickness (cIMT). High LDL and high blood pressure were significantly associated with increased carotid intima-media thickness in children on dialysis.
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