Key result
Slow deep breathing training with soothing music significantly improved heart rate variability (RMSSD) compared to simple chest expansion in patients with type 2 diabetes and cardiac autonomic neuropathy.
Why the study?
This study aimed to investigate the effects of slow deep breathing on heart rate variability in patients with type 2 diabetes mellitus and cardiovascular autonomic neuropathy.
Does slow deep breathing training improve heart rate variability in patients with type 2 diabetes mellitus and cardiovascular autonomic neuropathy?
Population
Sixty patients with CAN secondary to T2DM
Comparison
Slow deep breathing training with soothing music vs control
Design
Randomized controlled trial
Follow-up
3 months
Authors
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May offer low-cost adjunct for diabetic autonomic neuropathy; hypothesis-generating pending larger trials.
RCT (n=60)
Random number table
No
Does slow deep breathing training improve heart rate variability in patients with type 2 diabetes mellitus and cardiovascular autonomic neuropathy?
p-value: p=0.013
Sustained slow deep breathing training significantly improves heart rate variability in patients with type 2 diabetes mellitus and cardiac autonomic neuropathy, offering a non-invasive adjunctive therapy.
Xuan et al. (2025) conducted an RCT in Type 2 diabetes mellitus with cardiovascular autonomic neuropathy (n=60). Slow deep breathing (SDB) training with soothing music vs. Simple chest expansion training for 20 min once daily was evaluated on RMSSD (square root of the mean squared differences of successive RR) (p=0.013). Slow deep breathing training with soothing music significantly improved heart rate variability (RMSSD) compared to simple chest expansion in patients with type 2 diabetes and cardiac autonomic neuropathy.
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