Key result
Continuous perineural infusion of 0.2% ropivacaine significantly reduced postoperative pain scores at 24 hours (VAS 3.39 vs 5.03, p<0.001) compared to placebo in patients undergoing upper extremity orthopaedic surgery.
Why the study?
Does continuous infraclavicular brachial plexus block with ropivacaine improve postoperative pain control in patients undergoing upper extremity orthopaedic surgery?
RCT (n=60)
Double-blind
Randomized
No
Does continuous infraclavicular brachial plexus block with ropivacaine improve postoperative pain control in patients undergoing upper extremity orthopaedic surgery?
Absolute Event Rate: 3.39% vs 5.03%
p-value: p=<0.001
Continuous infraclavicular brachial plexus block with ropivacaine significantly reduces postoperative pain, sleep disturbances, and analgesic use after upper extremity orthopaedic surgery.
Supports continuous infraclavicular blocks for upper extremity surgery; confirms RCT efficacy of perineural ropivacaine for acute pain.
This study was aimed to assess the efficacy of patient controlled analgesia using continuous infraclavicular brachial plexus in upper limb surgeries, to study the amount of rescue analgesics used and to study the associated complications and sleep disturbances in patients underwent upper extremity orthopaedic surgery. MATERIALS AND METHODSA prospective randomized clinical study was done on 60 patients undergoing upper limb below mid shaft of humerus surgeries.Sixty patients belonging to ASA-Physical status 1-2 were selected for study and randomly allocated to two groups of 30 each.Group A received patient controlled analgesia with continuous infusion of 0.2% ropivacaine through infraclavicular catheter (P Group).Group B received patient controlled analgesia with continuous infusion of 0.9% normal saline through infraclavicular catheter (C Group). RESULTSPatients received ropivacaine experienced significantly less postoperative pain compared with patients received normal saline during rest at all-time intervals except at the baseline.Patients in the C group received first top-up in 5-6 hours, whereas 6 patients in the P group received their first top-up after 10 hours and 22 patients received after 12 hours.In the Group P, patients experienced no sleep disturbances compared to the placebo group. CONCLUSIONThis randomized, double-blinded, placebo-controlled study shows us that postoperative analgesia is achievable using a perineural infusion of ropivacaine via an infraclavicular brachial plexus catheter after moderately painful upper extremity surgery.Hence, patients experienced a significant decrease in sleep disturbances, analgesic use and narcotic-related side effects.
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Aboobacker et al. (2015) conducted an RCT in Postoperative pain after upper extremity orthopaedic surgery (n=60). Continuous infraclavicular brachial plexus block with 0.2% ropivacaine vs. 0.9% normal saline continuous infusion was evaluated on Postoperative pain score (VAS) at 24 hours (p=<0.001). Continuous perineural infusion of 0.2% ropivacaine significantly reduced postoperative pain scores at 24 hours (VAS 3.39 vs 5.03, p<0.001) compared to placebo in patients undergoing upper extremity orthopaedic surgery.
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