Key result
Administration of neuromuscular blocking agents, corticosteroids, and antibiotics in a 16-month-old child with acute respiratory insufficiency was followed by severe acute quadriplegic myopathy.
Case Report (n=1)
Highlights the risk of acute quadriplegic myopathy in pediatric patients receiving neuromuscular blocking agents and corticosteroids during mechanical ventilation.
May warrant vigilance for myopathy in ventilated infants on these agents; single case leaves open causality and generalizability.
We present a case of a 16-month old previously healthy child who was hospitalized because of an acute respiratory insufficiency most likely caused by a viral infection and who then developed a severe acute quadriplegic myopathy (AQM). Initial clinical symptoms were respiratory acidosis, dypnea, intense wheezing, and deterioration of the level of consciousness, which required orotracheal intubation and mechanical ventilation. We administered neuromuscular blocking agents, corticosteroids, and antibiotics. After 9 days the clinical picture improved. An attempt to wean from the ventilator failed. We diagnosed AQM. This paper discusses AQM and its clinical importance.
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Iodice et al. (2005) conducted a case report in Acute quadriplegic myopathy (n=1). Neuromuscular blocking agents, corticosteroids, and antibiotics was evaluated on Development of acute quadriplegic myopathy and failure to wean from ventilator. Administration of neuromuscular blocking agents, corticosteroids, and antibiotics in a 16-month-old child with acute respiratory insufficiency was followed by severe acute quadriplegic myopathy.
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