Key result
Phylogeographic analysis of 489 FMDV O/EA-3 sequences revealed a mean substitution rate of 6.64 × 10−3 nt/site/year and identified Sudan as a major source of transboundary viral spread.
Why the study?
The success of FMD control programs depends on understanding viral spread dynamics following recent 2018 and 2019 outbreaks in North-Western Africa.
Observational (n=489)
The study identifies key transboundary migration routes of the FMDV O/EA-3 topotype from Sudan to other regions in Africa and Western Asia, highlighting the need for inter-regional surveillance.
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Sudan-linked routes warrant prioritized surveillance; leaves open targeted control efficacy in prospective studies.
Canini et al. (2022) conducted an observational in Foot-and-mouth disease (FMD) (n=489). FMDV O/EA-3 topotype was evaluated on Mean substitution rate and migration routes. Phylogeographic analysis of 489 FMDV O/EA-3 sequences revealed a mean substitution rate of 6.64 × 10−3 nt/site/year and identified Sudan as a major source of transboundary viral spread.
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