Key result
Perioperative maternal hypotension during cesarean delivery with spinal anesthesia did not significantly affect the newborn perfusion index compared to no hypotension (2.724 vs 2.924, p=0.455).
Why the study?
Perfusion index serves as a rapid indicator of microcirculatory changes, prompting evaluation of how perioperative hypotension during cesarean delivery under spinal anesthesia affects infant perfusion index.
Does maternal hypotension requiring ephedrine during cesarean section affect the perfusion index and pleth variability index in newborns?
Observational (n=50)
No
Does maternal hypotension requiring ephedrine during cesarean section affect the perfusion index and pleth variability index in newborns?
Absolute Event Rate: 2.724% vs 2.924%
p-value: p=0.455
Maternal hypotension during cesarean section, when rapidly treated with fluid replacement and ephedrine, does not significantly alter newborn perfusion index or Apgar scores.
Maternal ephedrine for spinal hypotension may alter newborn PI; leaves open clinical relevance and need for outcome studies.
Aim: The perfusion index (PI) is maintained as the rate of pulsatile blood flow to nonpulsatile flow in the peripheral extremity and is used as a rapid indicator of microcirculatory changes. Material and Methods: Fifty patients a gestational age of 38-42 weeks and a planned elective cesarean were included in our study. Patients who did not develop hypotension after spinal anesthesia and were not administered ephedrine (Group 1) and newborn patients who developed hypotension and needed ephedrine (Group 2) were divided into 2 groups. Results: There was no statistical difference in PVI and PI measurements between Group1 and Group 2. Discussion: Negative effects on PI, PVI and APGAR scores that may develop in the newborn can be prevented with rapid and adequate fluid replacement and appropriate vasoconstrictive treatment.
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A 2022 study conducted an observational in Elective cesarean delivery with spinal anesthesia (n=50). Perioperative maternal hypotension vs. No maternal hypotension was evaluated on Newborn Perfusion Index (PI) (p=0.455). Perioperative maternal hypotension during cesarean delivery with spinal anesthesia did not significantly affect the newborn perfusion index compared to no hypotension (2.724 vs 2.924, p=0.455).
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