Key result
This review summarizes recent data on the pathogenic mechanisms, risk factors, biomarkers, diagnosis, and prevention of cardiovascular diseases in patients with rheumatoid arthritis.
This review highlights the critical role of cardiovascular diseases as the primary cause of comorbidity and mortality in rheumatoid arthritis patients, emphasizing the need for targeted diagnosis and prevention.
Integrates RA-CVD inflammatory pathways and biomarkers; leaves open RA-specific risk models for prospective validation.
Cardiovascular diseases (CVD) in patients with rheumatoid arthritis (RA) are ranked first in the structure of comorbidity and mortality. This review includes recent data on common pathogenic mechanisms of inflammation and atherosclerosis, the impact of traditional and specific risk factors, biomarkers of CVD in RA patients. Variants of CVD in RA, the possible pathogenic mechanisms of their development and methods of diagnosis and prevention are described.
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Gasparyan et al. (2016) conducted a review in Rheumatoid arthritis and cardiovascular diseases. This review summarizes recent data on the pathogenic mechanisms, risk factors, biomarkers, diagnosis, and prevention of cardiovascular diseases in patients with rheumatoid arthritis.
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