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Classification The major morphological classifications (WHO/ AFIP; modified Mainz classification, and the Heidelberg classification) discriminate eight sub-types of renal cell tumors related to the basic cell types of the nephron from which they are derived, and in line with the genetic facts as presently understood: 1) metanephric adenoma and metanephric adenofibroma, 2) papillary adenoma, 3) renal oncocytoma, all three benign parenchymal neoplasms Malignant parenchymal neoplasms are: 4) common or conventional (clear cell) renal carcinoma, 5) papillary (formerly chromophilic or tubulopapillary) renal carcinoma, 6) chromophobe renal carcinoma, 7) collecting duct carcinoma, and 8) renal cell carcinoma, unclassified.
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Berg et al. (2011) studied this question.
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