Key result
Diabetes is associated with a 10-year risk of macrovascular complications that is four times higher than that of microvascular complications, with coronary artery disease as the leading cause of death.
Diabetes represents a major and growing global health burden, with macrovascular complications like coronary artery disease driving mortality, especially in women.
Emphasizes macrovascular risk reduction in diabetes care; leaves open the need for targeted trials on CAD prevention.
iabetes is a metabolic disease whose incidence and prevalence has significantly increased in recent decades, mainly because of an increase in type 2 diabetes, which represents almost 90% of all cases of diabetes. The World Health Organization estimates that, by 2025, there will be 300 million diabetic patients (5.4% of the world population). Older patients are most affected by diabetes, as the disease prevalence increases with age, at least up until 75 years. The progressive aging of the global population could explain about half of the predicted increase of diabetic patients in the near future. In the UK prospective diabetes study (UKPDS), 2 the 10 year risk of all macrovascular complications was four times that of microvascular complications. Coronary artery disease is the leading cause of death among diabetic patients, and women have a higher cardiovascular risk than men.
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Pedro Monteiro (2005) conducted a review in Diabetes. Diabetes was evaluated. Diabetes is associated with a 10-year risk of macrovascular complications that is four times higher than that of microvascular complications, with coronary artery disease as the leading cause of death.
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