Key result
A 73-year-old female with a spindle-cell sarcoma of the popliteal fossa, initially mimicking a benign venous angioma, remained free of local recurrence or metastatic disease 3 years after amputation.
Case Report (n=1)
No
Spindle-cell sarcomas can present with a long indolent course and mimic benign vascular lesions on MRI, requiring careful follow-up and biopsy for definitive diagnosis.
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Popliteal lesions mimicking angiomas require biopsy to exclude sarcoma; this case extends the spectrum of indolent presentations but leaves optimal strategies open.
Spindle-cell sarcomas are a group of aggressive malignant soft-tissue tumors with diverse clinical presentations. While some of these tumors may represent de novo malignant transformation of benign entities, others may present with a long indolent course before their invasive nature is apparent. We report the case of a previously healthy 73-year-old female with spindle-cell sarcoma of the left popliteal fossa who initially presented with a painless mass of several months' duration. Magnetic resonance imaging (MRI) suggested a benign vascular lesion/venous angioma, but after the patient's clinical course changed, repeat MRI 18 months later was consistent with an infiltrative soft-tissue malignancy/sarcoma. Excisional biopsy revealed a stage II spindle-cell sarcoma. The patient then underwent radiotherapy and subsequent above-the-knee amputation. Three years following the amputation, the patient is free of local tumor recurrence or metastatic disease.
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Nissim et al. (2010) conducted a case report in Spindle-cell sarcoma (n=1). Excisional biopsy, radiotherapy, and above-the-knee amputation was evaluated on Tumor recurrence or metastatic disease. A 73-year-old female with a spindle-cell sarcoma of the popliteal fossa, initially mimicking a benign venous angioma, remained free of local recurrence or metastatic disease 3 years after amputation.
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