A molecular conga line! Chlorin e6, a second-generation photosensitizer, was conjugated with angiogenin and a DNA aptamer to create a novel drug delivery system for photodynamic therapy (PDT). The results show that the photosensitizer is delivered to and internalized by the target cells with high specificity and excellent efficiency. After irradiation by an appropriate light source, the conjugate showed high efficiency and promise as a PDT agent.
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Yang et al. (2011) studied this question.
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