Chemotherapeutic management of epidural neuroblastoma

Nine children with neuroblastoma and spinal cord compression were managed initially with chemotherapy induction without laminectomy or radiotherapy. Of the nine children seven are neurologically normal, one has minimal residual deficits, and one remains paraplegic. The excellent results in these children, plus nine patients previously reported, emphasizes the validity of this approach in children with epidural extension of neuroblastoma.