Key result
A novel fourth-generation atrial exclusion device achieved safe left atrial appendage exclusion in 15 mongrel dogs, with 100% left circumflex artery patency up to 6 months.
Why the study?
Does a novel fourth-generation atrial exclusion device achieve safe and effective left atrial appendage occlusion in a canine model?
Does a novel fourth-generation atrial exclusion device achieve safe and effective left atrial appendage occlusion in a canine model?
A novel fourth-generation atrial exclusion device demonstrated feasibility, safety, and favorable histological healing in a canine model, suggesting potential for clinical application in stroke prevention for atrial fibrillation.
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Does not warrant clinical use; hypothesis-generating for human translation of fourth-generation device.
Fumoto et al. (2012) studied atrial fibrillation (n=15). fourth-generation atrial exclusion device was evaluated on feasibility and efficacy of left atrial appendage exclusion. A novel fourth-generation atrial exclusion device achieved safe left atrial appendage exclusion in 15 mongrel dogs, with 100% left circumflex artery patency up to 6 months.
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