Key result
Milder spinal muscular atrophy types and emotional distress were associated with reduced mental quality of life, explaining 10% and 45% of the variance in mental component scores, respectively.
Cross-Sectional (n=62)
In adult patients with SMA, emotional distress is a major determinant of both mental and physical quality of life, suggesting psychological interventions may be beneficial.
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Emotional distress may merit screening in SMA; leaves open whether interventions improve quality of life.
Reenen et al. (2016) conducted a cross-sectional in Spinal muscular atrophy (n=62). Spinal muscular atrophy type and emotional distress vs. Healthy reference population was evaluated on Physical component scores (PCS) and mental component scores (MCS) of the SF-36. Milder spinal muscular atrophy types and emotional distress were associated with reduced mental quality of life, explaining 10% and 45% of the variance in mental component scores, respectively.
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