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Coded messages: Lanthanide (Ln) coded protease-specific peptide–nanoparticle (NPs) conjugates act as probes for a multiplex protease assay (MPA) using inductively coupled plasma mass spectrometry (ICP-MS; see picture). MPA can be achieved by centrifugal separation of the protease-cleaved and uncleaved probes and subsequent determination of the released Ln tags.
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Yan et al. (2011) studied this question.
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