Key result
Integrated cardio-oncology services optimize cancer therapy completion while minimizing cardiovascular toxicity.
Why the study?
Cancer and cardiovascular disease increasingly intersect in clinical practice, creating a need for pragmatic blueprints to guide integrated cardio-oncology services.
An integrated cardio-oncology service incorporating multidisciplinary care, standardized risk assessment, and active surveillance provides a scalable blueprint to mitigate cardiovascular toxicity while maintaining optimal cancer therapy.
May guide cardio-oncology service design; leaves open prospective validation of clinical outcomes.
Cancer and cardiovascular disease increasingly intersect in clinical practice. An integrated cardio-oncology service is a coordinated, multidisciplinary programme that embeds cardiovascular risk assessment, on-treatment surveillance and post-treatment follow-up within routine cancer care, supported by shared protocols and decision-making. The aim of such services is to maintain the delivery of best-practice cancer therapy while preventing and treating cardiovascular toxicity. This review distils pragmatic, transferable elements for cardiac and oncology teams: a unified programme with risk-based streaming; nurse-enabled triage and surveillance; pharmacist-led drug-drug interaction stewardship and medication optimisation; fast-track imaging and cardiology access; and clear triggers for escalation that minimise unnecessary cancer therapy interruption. The goal for this review is to provide a pragmatic blueprint for such services, illustrated by international models and our Newcastle bench-to-bedside experience.
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Butel-Simoes et al. (2026) conducted a review in Cancer and cardiovascular disease. Integrated cardio-oncology service was evaluated. An integrated cardio-oncology service provides a multidisciplinary, structured approach to risk assessment, surveillance, and management to maintain cancer therapy while preventing cardiovascular toxicity.
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