This article is a chapter in the ISPAD Clinical Practice Consensus Guidelines 2014 Compendium.The complete set of guidelines can be found for free download at www.ispad.org.The evidence grading system used in the ISPAD Guidelines is the same as that used by the American Diabetes Association.See page 3 (the Introduction in Pediatric Diabetes 2014; 15 (Suppl.20): 1-3).symptoms (i.e., hypoglycemia unawareness).• Blood glucose goals may need to be adjusted upward in patients with recurrent hypoglycemia and/or hypoglycemia unawareness (B).• If unexplained hypoglycemia is frequent, evaluation for unrecognized celiac and Addison's disease should be considered (E).
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