Why the study?
Does a single dose of 20 mg intravenous metoclopramide reduce the presence of a full stomach before anesthesia in adult patients admitted for emergency major orthopedic surgery?
Does a single dose of 20 mg intravenous metoclopramide reduce the presence of a full stomach before anesthesia in adult patients admitted for emergency major orthopedic surgery?
A single 20 mg intravenous dose of metoclopramide given at least 90 minutes before premedication significantly reduces the incidence of a full stomach prior to anesthesia in emergency orthopedic surgery patients.
Supports metoclopramide use before emergency orthopedic anesthesia to lower aspiration risk; extends prokinetic evidence to urgent surgical settings.
Sixty adult patients admitted for emergency major orthopedic surgery were studied according to a double-blind, randomized design in order to evaluate if a single dose of 20 mg metoclopramide given intravenously at least 90 min before premedication could evacuate the stomach before anesthesia. Three patients were excluded. X-ray examination following intake of barium sulfate before anesthesia showed 10 patients with a full stomach, all belonging to the placebo group. This study demonstrates significantly fewer (P less than 0.002) patients with a full stomach before anesthesia after metoclopramide, indicating that administration of metoclopramide reduces the risk of aspiration of gastric contents to the lungs during anesthesia.
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Adelhøj et al. (1985) studied this question.
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