Why the study?
Does prophylactic ondansetron reduce postoperative nausea and vomiting compared to metoclopramide in patients undergoing major neurosurgical procedures?
Does prophylactic ondansetron reduce postoperative nausea and vomiting compared to metoclopramide in patients undergoing major neurosurgical procedures?
Prophylactic metoclopramide is more effective than ondansetron in reducing postoperative nausea and vomiting following major neurosurgical procedures.
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Favors metoclopramide over ondansetron for PONV prophylaxis after neurosurgery; extends RCT comparisons to this high-risk population.
Pugh et al. (1996) studied this question.
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