Key result
Higher red cell distribution width was an independent predictor of a high GRACE score (OR 1.513; 95% CI 1.116-2.051; P=0.008) and was associated with increased in-hospital mortality.
Why the study?
Does red cell distribution width (RDW) predict high GRACE risk score and in-hospital mortality in patients with UAP/NSTEMI?
Cohort (n=193)
Does red cell distribution width (RDW) predict high GRACE risk score and in-hospital mortality in patients with UAP/NSTEMI?
Odds Ratio: 1.513 (95% CI 1.116–2.051)
p-value: p=0.008
High red cell distribution width is an independent predictor of a high GRACE score and is associated with in-hospital mortality in patients with UAP/NSTEMI.
RDW may refine in-hospital risk stratification in UAP/NSTEMI; leaves open its incremental value beyond GRACE in prospective studies.
The aim of this study was to evaluate the relationship between red cell distribution width (RDW) and Global Registry of Acute Coronary Events (GRACE) risk score in patients with unstable angina pectoris (UAP) and non-ST elevation myocardial infarction (NSTEMI). We retrospectively enrolled 193 patients with UAP/NSTEMI (mean age 63.6 ± 12.6 years; men 57%) in this study. Higher RDW values were associated with increased in-hospital mortality (P = .001). There is a significant correlation between RDW and GRACE score (P < .001). In multivariate logistic regression analysis, RDW was found to be an independent predictor of high GRACE score (odds ratio: 1.513, 95% confidence interval: 1.116-2.051, P = .008). A cutoff value of >15.74 for RDW predicted high GRACE score, with a 64% sensitivity and 65% specificity. Our study results demonstrated that high RDW was an independent predictor of high GRACE score, and it is associated with in-hospital mortality in UAP/NSTEMI.
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Polat et al. (2013) conducted a cohort in Unstable angina pectoris (UAP) and non-ST elevation myocardial infarction (NSTEMI) (n=193). Red cell distribution width (RDW) was evaluated on High GRACE score (OR 1.513, 95% CI 1.116-2.051, p=0.008). Higher red cell distribution width was an independent predictor of a high GRACE score (OR 1.513; 95% CI 1.116-2.051; P=0.008) and was associated with increased in-hospital mortality.
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