Key result
High-dose corticosteroid pulse therapy combined with mechanical circulatory support led to rapid resolution of cardiogenic shock and recovery of cardiac function in three young adults with MIS-A.
Why the study?
Multisystem inflammatory syndrome associated with SARS-CoV-2 infection can present with myocarditis complicated by cardiogenic shock, but few case reports describe MIS in adults.
Population
Three healthy young adults with SARS-CoV-2-related MIS-A and cardiogenic shock secondary to myocarditis
Design
Case series
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May support steroids plus MCS in refractory MIS-A shock; hypothesis-generating and should not change practice.
Case Report (n=3)
No
High-dose corticosteroid pulse therapy and mechanical circulatory support appear effective in managing fulminant myocarditis and cardiogenic shock associated with SARS-CoV-2 MIS-A.
A 2022 study conducted a case report in Multisystem Inflammatory Syndrome in Adults (MIS-A) associated with COVID-19 (n=3). High-dose corticosteroid pulse therapy and mechanical circulatory support was evaluated on Resolution of cardiogenic shock and recovery of cardiac function. High-dose corticosteroid pulse therapy combined with mechanical circulatory support led to rapid resolution of cardiogenic shock and recovery of cardiac function in three young adults with MIS-A.
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