Key result
Post-COVID myocarditis was associated with long-term persistence of SARS-Cov-2 in the myocardium (up to 9 months) and high immune activity, presenting as arrhythmic or decompensated variants.
Why the study?
Clinical features and possible mechanisms of myoendocarditis, including SARS-CoV-2 persistence in the myocardium in the long-term period after COVID-19, needed investigation.
Population
15 patients aged 47.8±13.4 years with post-COVID myocarditis
Design
Prospective cohort study
Authors
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May prompt extended surveillance in symptomatic cases; leaves open antiviral trials targeting myocardial persistence.
Cohort (n=15)
Subacute and chronic post-COVID myocarditis is associated with long-term persistence of SARS-CoV-2 in the myocardium and high immune activity, presenting as either isolated arrhythmias or systolic dysfunction.
Благова et al. (2021) conducted a cohort in post-COVID myocarditis (n=15). SARS-Cov-2 infection was evaluated on Clinical features and mechanisms of post-COVID myoendocarditis. Post-COVID myocarditis was associated with long-term persistence of SARS-Cov-2 in the myocardium (up to 9 months) and high immune activity, presenting as arrhythmic or decompensated variants.
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