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November 11, 2024Philippine journal of cardiology.Open Access

Predictors of In-hospital and Short-term Outcomes of Thoracic Endovascular Aortic Repair for Aortic Aneurysm and Aortic Syndrome: A Single-Center Experience

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Key result

In patients undergoing thoracic endovascular aortic repair, preexisting chronic kidney disease was a significant independent predictor of in-hospital mortality and major adverse events (OR 10.33).

Why the study?

TEVAR was not widely practiced locally until 2017, and predictors of in-hospital and short-term outcomes in this setting were needed to compare with local and international data.

Population

52 adult patients undergoing TEVAR for aortic aneurysm and aortic syndrome

Comparison

Predictors of in-hospital mortality and major adverse events

Design

Single-center retrospective analysis

Follow-up

1 year

Authors

NANiña Carissa L Alegado-AsenieroRORowena OnaJMJeffrey Mendoza

Discussion

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Member takes

Overview

CKD predicts higher in-hospital mortality after TEVAR; hypothesis-generating for risk stratification and requires prospective validation.

Study Design

Type

Cohort (n=52)

Multicenter

No

Structured PICO

P
Population
52 adult patients (mean age 65.7 years, 25% female) with aortic aneurysm or aortic syndrome who underwent thoracic endovascular aortic repair at a single center in the Philippines, followed for up to 1 year.
E
Exposure
Thoracic endovascular aortic repair (TEVAR)
O
Outcome
In-hospital mortality and development of major adverse events (MAEs)hard clinical

Main Result

Odds Ratio: 10.33 (95% CI 1.1069–96.462)

p-value: p=0.040

In patients undergoing TEVAR, increasing weight, preexisting chronic kidney disease, and single-stage debranching are independent predictors of in-hospital mortality and major adverse events.

Limitations

  • Retrospective design prone to recall bias and missing data bias
  • Small sample size
  • Single-center study
  • Short follow-up period

Cite This Study

Alegado-Aseniero et al. (2024) conducted a cohort in Aortic aneurysm and aortic syndrome (n=52). Preexisting chronic kidney disease vs. No chronic kidney disease was evaluated on In-hospital mortality and major adverse events (MAEs) (OR 10.33, 95% CI 1.1069-96.462, p=0.040). In patients undergoing thoracic endovascular aortic repair, preexisting chronic kidney disease was a significant independent predictor of in-hospital mortality and major adverse events (OR 10.33).

synapsesocial.com/papers/6a983e4bb14ffd067bd7d436https://doi.org/10.69944/pjc.41d3aa981b
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Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Risk Factors of Early and Late Mortality After Thoracic Endovascular Aortic Repair for Complicated Stanford B Acute Aortic Dissection2014 · 21 citations
  2. 2Risk Factors Associated With Reintervention After Thoracic Endovascular Aortic Repair for Descending Aortic Pathologies2018 · 11 citations