An esterase toolbox: A set of isoenzymes of pig liver esterases (PLE) is identified, cloned, and overexpressed in E. coli. They show striking differences in enantioselectivity and enantiopreference in the kinetic resolution of acetates of secondary alcohols as well as the desymmetrization of cis-3,5-diacetoxycyclopent-1-ene to 1 a and 1 b (see picture: enantiopreference of the new isoenzymes and a commercial PLE isoenzyme mixture).
No takes yet. Share an insight, caveat, or question.
Hummel et al. (2007) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: