Some aldol condensation reactions proceeded more efficiently and stereoselectively in the absence of solvent than in solution. When the aldol reaction was carried in an inclusion complex with an optically active host compound, diastereo- and enantio-selective reaction occurred.
No takes yet. Share an insight, caveat, or question.
Toda et al. (1990) studied this question.
Synapse has enriched 5 related papers. Consider them for comparative context: