Why the study?
Does prophylactic amantadine hydrochloride reduce the occurrence and severity of experimentally induced Asian influenza in volunteers?
Population
58 volunteers with experimentally induced Asian influenza (a2/Rockville/1/65 strain)
Comparison
Prophylactic administration of amantadine… vs Control subjects
Design
RCT, Double-blind
Authors
Loading...
Supports prophylactic amantadine during influenza exposure; confirms efficacy in controlled volunteer studies and supports evaluation in natural outbreaks.
Does prophylactic amantadine hydrochloride reduce the occurrence and severity of experimentally induced Asian influenza in volunteers?
Prophylactic amantadine hydrochloride significantly reduces the occurrence and severity of experimentally induced Asian influenza.
Y. Togo (1968) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: