Key result
Maternal diabetes mellitus was associated with a 24% prevalence of pathological congenital heart diseases in infants, most commonly ventricular septal defect, patent ductus arteriosus, and hypertrophic cardiomyopathy.
Why the study?
Despite advances in perinatal care, infants of diabetic mothers remain at increased risk for structural lesions and functional cardiac changes.
Does maternal diabetes mellitus increase the prevalence of echocardiographic abnormalities in neonates?
Comparison
Infants of diabetic mothers vs matched controls
Design
Retrospective analytical study
Authors
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Echocardiographic abnormalities may be more frequent in IDMs; leaves open whether routine screening improves outcomes.
Observational (n=200)
No
Does maternal diabetes mellitus increase the prevalence of echocardiographic abnormalities in neonates?
Infants of diabetic mothers have a high prevalence (24%) of structural congenital cardiac anomalies, underscoring the clinical importance of routine early echocardiographic screening in this population.
Samir et al. (2025) conducted an observational in Congenital heart disease in infants of diabetic mothers (n=200). Maternal diabetes mellitus vs. Non-diabetic mothers was evaluated on Prevalence of pathological congenital heart diseases. Maternal diabetes mellitus was associated with a 24% prevalence of pathological congenital heart diseases in infants, most commonly ventricular septal defect, patent ductus arteriosus, and hypertrophic cardiomyopathy.
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