Key result
Thrombophilia testing in children should be individualized, with adolescents experiencing spontaneous thrombosis and teenage females with a positive family history most likely to benefit.
Population
Children with symptomatic thrombosis, or asymptomatic children who have relatives affected with either…
Design
Review
Authors
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Supports selective testing in high-yield pediatric subgroups; leaves open need for prospective validation before broader adoption.
Thrombophilia testing in children should be individualized, with the highest potential benefit in adolescents with spontaneous thrombosis or teenage females with a family history considering contraception.
Leslie Raffini (2008) conducted a review in Thrombosis and thrombophilia. Thrombophilia testing was evaluated. Thrombophilia testing in children should be individualized, with adolescents experiencing spontaneous thrombosis and teenage females with a positive family history most likely to benefit.
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