Why the study?
How do shunt size, vascular resistances, and heart rate affect cardiovascular dynamics and oxygenation in a computational model of the Norwood circulation?
Population
Computational model of the Norwood circulation for hypoplastic left heart syndrome
Design
Preclinical
Authors
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Should not guide clinical Norwood management; leaves open prospective validation of Qp/Qs targets.
How do shunt size, vascular resistances, and heart rate affect cardiovascular dynamics and oxygenation in a computational model of the Norwood circulation?
In a computational model of the Norwood circulation, a pulmonary-to-systemic blood flow ratio of 1 optimizes oxygen delivery across various physiological states and shunt sizes.
Migliavacca et al. (2001) studied this question.
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