Key result
Immediate complete revascularization in STEMI patients reduced recurrent MI and repeat revascularization compared to a staged approach, with no difference in mortality or bleeding.
Why the study?
Does immediate complete revascularization reduce mortality, bleeding, recurrent MI, or revascularization compared to staged revascularization in STEMI patients with multivessel disease?
Does immediate complete revascularization reduce mortality, bleeding, recurrent MI, or revascularization compared to staged revascularization in STEMI patients with multivessel disease?
Immediate complete revascularization in STEMI with multivessel disease reduces recurrent MI and need for revascularization without increasing bleeding or mortality compared to a staged approach.
May support immediate complete revascularization to reduce recurrent events; hypothesis-generating from Level 5 data, RCTs needed.
Two randomized trials compared immediate complete revascularization versus staged revascularization in STEMI patients with multivessel disease and found no difference in mortality or bleeding but reduced recurrent MI and revascularization with immediate approach.
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Kastrati et al. (2024) studied this question. Immediate complete revascularization in STEMI patients reduced recurrent MI and repeat revascularization compared to a staged approach, with no difference in mortality or bleeding.
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