Key result
In patients with acute stroke, increased arterial stiffness was significantly associated with higher HbA1c, total cholesterol, central blood pressures, and a higher prevalence of diabetes mellitus.
Why the study?
Does increased arterial stiffness correlate with cardiovascular risk factors in patients with acute stroke?
Cross-Sectional (n=114)
No
Does increased arterial stiffness correlate with cardiovascular risk factors in patients with acute stroke?
Absolute Event Rate: 6.61% vs 6.18%
p-value: p=0.032
Increased arterial stiffness measured by baPWV in acute stroke patients is significantly associated with higher HbA1c, total cholesterol, central blood pressures, and diabetes prevalence, suggesting the importance of managing these risk factors to improve prognosis.
No immediate practice change; leaves open causal role of stiffness in stroke outcomes.
Pulse wave velocity (PWV) is used to non-invasively estimate the severity of arteriosclerosis by measuring the patient's arterial stiffness comparing with each normal reference range according to their ages. Increased arterial stiffness is closely related to both atherosclerosis and arteriosclerosis, which have been known for causes of cardiovascular disease and stroke, also negatively affects the prognosis and the re-occurrence in patients with stroke. The study is focused on how brachial-ankle pulse wave velocity (baPWV) is related to cardiovascular disease risk factors in patients with acute stroke. There were 114 subjects, 69 males and 45 females, all in their 60's and had PWV test for acute stroke. The results are as follows: the group with increased arterial stiffness showed significant increase in HbAlc, total cholesterol, RSBP (resting systolic blood pressure), CSBP (central systolic blood pressure) and CDBP (central diastolic blood pressure). Cross tabulation test showed that there was a significant relationship only between the group with increased arterial stiffness and diabetes mellitus (DM). Therefore, it might be useful for preventing re-occurrence and making a favorable prognosis to promptly adjust DM and hypertension-related risk factors in patients with acute stroke.
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Jin et al. (2014) conducted a cross-sectional in Acute ischemic stroke or transient ischemic attack (n=114). Increased arterial stiffness (abnormal baPWV) vs. Normal arterial stiffness was evaluated on HbA1c (p=0.032). In patients with acute stroke, increased arterial stiffness was significantly associated with higher HbA1c, total cholesterol, central blood pressures, and a higher prevalence of diabetes mellitus.
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