Highlights the clinical scenario of managing thromboembolism risk in a pregnant patient with hereditary protein S deficiency undergoing emergency surgery.
Protein S is a nonenzymatic and vitamin K-dependent cofactor of activated protein C. Without protein S, the anticoagulant function of protein C is almost depleted and thrombotic events occur. We report a parturient with hereditary protein S deficiency in whom the risk of thromboembolism was further complicated by pregnancy and who required emergency Caesarean section for fetal distress.
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Fan et al. (1995) studied this question.
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