Key result
Expression of ANGPTL4 in human gastric cancer was significantly correlated with venous invasion (p<0.00005), lymph node metastasis (p<0.001), and advanced TNM stage (p<0.001).
Population
103 primary human gastric adenocarcinomas surgically resected at Nagasaki University Hospital between 1998…
Design
Cohort
Follow-up
median 1301 days for disease-free patients
Authors
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May identify higher metastatic risk in gastric cancer; leaves open its value as biomarker or target.
Observational (n=103)
No
p-value: p=<0.00005
ANGPTL4 expression in human gastric cancer is significantly associated with venous invasion and tumor progression, suggesting it plays a role in the metastatic process.
Takeo Nakayama (2010) conducted an observational in Gastric cancer (n=103). ANGPTL4 expression vs. Negative ANGPTL4 expression was evaluated on Venous invasion (p=<0.00005). Expression of ANGPTL4 in human gastric cancer was significantly correlated with venous invasion (p<0.00005), lymph node metastasis (p<0.001), and advanced TNM stage (p<0.001).
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