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The immobilization and controlled release of salicylic acid (SA) in chitosan/poly(lactic acid) (Ch/LA) blends were studied in the present work. The Ch/PLA bland’s morphology was studied by SEM. FT-IR and DSC were used to investigate the interactions between the polymer matrix and the SA. The SA release kinetics was interpreted by the Weibull and Higuchi models. The SA release was the fastest in Ch/PLA systems with inhomogeneous and porous structure. It was slower in neat PLA matrix due to its dense structure and hydrophobic behavior, and in neat chitosan matrix, because of specific electrostatic chitosan/SA interactions and complex formation.
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Marudova et al. (2018) studied this question.
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