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Localizes encephalitogenic activity to proteolipides in mice; leaves open translation to human demyelinating disease mechanisms.
ConclusionProteolipide A and B of Folch and Lees, a new group of lipoproteins, are capable of bringing about in mice acute disseminated encephalomyelitis indistinguishable from the affection induced by inoculation of whole brain tissue. The substance contains practically all of the encephalitogenic agent present in brain.
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Olitsky et al. (1952) studied this question.
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