Key result
A rupture-oriented surgical strategy for acute type A aortic dissection yielded similar in-hospital mortality between ascending aorta and aortic arch replacement groups (13.8% vs 14.7%, p=0.9).
Why the study?
The study was conducted to evaluate the immediate and long-term results of surgical treatment of acute aortic dissection type A using a rupture-oriented strategy.
Does a rupture-oriented surgical strategy (tailoring the extent of arch replacement to the site of intimal tear) provide comparable outcomes in patients with acute type A aortic dissection?
Cohort (n=157)
Does a rupture-oriented surgical strategy (tailoring the extent of arch replacement to the site of intimal tear) provide comparable outcomes in patients with acute type A aortic dissection?
A rupture-oriented surgical strategy for acute type A aortic dissection yields comparable immediate and long-term outcomes to more extensive arch replacement, offering a viable approach for less experienced centers.
May support rupture-oriented arch replacement in acute type A dissection; hypothesis-generating and requires randomized confirmation.
Objective. To evaluate the immediate and long-term results of surgical treatment of acute aortic dissection type A using rupture-oriented strategy. Material and methods. A prospective study included 157 patients with acute aortic dissection type A who were divided into 2 groups: group 1 — 123 people (inner wall rupture in ascending aorta or lesser curvature of aortic arch) underwent ascending aorta replacement and, if necessary, hemiarch procedure, group 2 — 34 patients (inner wall rupture in aortic arch (except for lesser curvature) or no rupture in ascending aorta and aortic arch, aortic arch aneurysm) underwent ascending aorta and aortic arch replacement. Early and late postoperative results were assessed. Results. In-hospital mortality was similar (13.8% and 14.7%, respectively, p=0.9). Early postoperative morbidity (bleeding, myocardial infarction, neurological complications, acute renal failure) was similar. Five-year survival rate was 74% and 82%, respectively (p=0.97), five-year freedom from redo aortic surgery — 88% and 90%, respectively (p=0.75). Conclusion. Rupture-oriented surgical strategy for acute aortic dissection type A may be used without worsening immediate and long-term results, especially in hospitals without extensive experience in aortic surgery.
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Kuznetsov et al. (2024) conducted a cohort in Acute type A aortic dissection (n=157). Ascending aorta replacement with or without hemiarch procedure vs. Ascending aorta and aortic arch replacement was evaluated on In-hospital mortality (p=0.9). A rupture-oriented surgical strategy for acute type A aortic dissection yielded similar in-hospital mortality between ascending aorta and aortic arch replacement groups (13.8% vs 14.7%, p=0.9).
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