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A study is made of the development of ovarian ova in mature rabbit does before and during various stages of pregnancy and after the injection of thyroid and anterior‐pituitary‐like hormones. No appreciable ovogenesis during sexual maturity was found. Nine types of ovarian follicle are distinguished according to size and degree of development. Full ovum size is reached in pre‐antral follicles, and is marked by the formation of a dictyate nucleus and slight reduction in nuclear size. Full follicle size is attained much later. The nature of follicle migration in the course of development is described. Ovum migration within the follicle is found to be a consequence of the nature of the egg's attachments to the follicular epithelium. The least atresia is found in young oocytes (10%), the larger follicles showing about 60% atretic at all stages of the reproductive cycle. The hormone preparations administered affect only the largest follicles and their contained ova.
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Pincus et al. (1937) studied this question.
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