The three-dimensional structure of uncomplexed natural sequence recombinant human growth hormone has been determined to 2.5 A. resolution by means of X-ray crystallographic techniques. The structure was solved using molecular replacement with a model of a hGH variant. The crystallographic refinement of the structure gave a final R-factor of 21.3% for data in the range from 8 to 2.5 A.
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Chantalat et al. (1995) studied this question.
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