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SummaryA cytopathogenic agent isolated from RPL 12 in chicken embryo liver tissue cultures is reported. The virus produces a marked CPE on liver parenchymal cells. Virus serially passed in tissue culture, when inoculated into susceptible chicks, produced visceral lymphomatosis. Neutralization tests with antiserum against RPL 12 indicate a relationship of tissue culture virus with RPL 12; however, positive identity of the cytopathogenic agent with the virus causing visceral lymphomatosis has not been established.
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Fontes et al. (1958) studied this question.
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