Key result
The highest quartile of urinary sodium excretion was associated with an increased risk of incident hypertension compared to the second quartile (Risk 1.26; 95% CI 1.01-1.57; P=0.043).
Why the study?
Does high 24-h urinary sodium excretion increase the risk of incident hypertension in middle-aged and elderly ethnic Chinese?
Population
1,520 middle-aged and elderly ethnic Chinese participants in Taiwan, free from hypertension at baseline…
Comparison
Highest quartile of 24-h urinary sodium excretion vs Second quartile or lowest quartile of 24-h…
Design
Cohort
Follow-up
median 7.93 years (IQR 4.07-9.04 years)
Authors
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May guide sodium monitoring in ethnic Chinese adults; extends J-shaped risk observations to Asian cohorts.
Cohort (n=1,520)
Does high 24-h urinary sodium excretion increase the risk of incident hypertension in middle-aged and elderly ethnic Chinese?
Relative Risk: 1.26 (95% CI 1.01–1.57)
p-value: p=0.043
High urinary sodium excretion exhibits a J-shaped association with incident hypertension in ethnic Chinese, extending the evidence of dietary sodium risk to Asian populations.
Chien et al. (2008) conducted a cohort in Hypertension (n=1,520). High urinary sodium excretion vs. Lower urinary sodium excretion was evaluated on Hypertension incidence (Risk 1.26, 95% CI 1.01-1.57, p=0.043). The highest quartile of urinary sodium excretion was associated with an increased risk of incident hypertension compared to the second quartile (Risk 1.26; 95% CI 1.01-1.57; P=0.043).
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