Transcatheter Aortic Valve Replacement for Severe Bicuspid Aortic Valve Stenosis

Figures

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  Figure 1. Preferred Reporting Items for Systematic Reviews and Meta-Analyses Flow Diagram Flow diagram illustrating study identification, screening, eligibility assessment, and inclusion in the meta-analysis.

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  Figure 2. Forest Plot for Moderate or Greater Paravalvular Leak (≥ Moderate) in Transcatheter Aortic Valve Replacement for Bicuspid vs Tricuspid Aortic Valve Stenosis Forest plot comparing the risk of moderate or greater paravalvular leak after transcatheter aortic valve replacement in bicuspid vs tricuspid aortic valve stenosis. BAV = bicuspid aortic valve; PVL = paravalvular leak; RR = risk ratio.

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  Figure 3. Forest Plot for Permanent Pacemaker Implantation in Transcatheter Aortic Valve Replacement for Bicuspid vs Tricuspid Aortic Valve Stenosis Forest plot comparing rates of permanent pacemaker implantation after transcatheter aortic valve replacement in bicuspid vs tricuspid aortic valve stenosis. PPM = permanent pacemaker implantation; other abbreviations as in Figure 2.

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  Figure 4. Forest Plot for Aortic Root Injury in Transcatheter Aortic Valve Replacement for Bicuspid vs Tricuspid Aortic Valve Stenosis Forest plot comparing the risk of aortic root injury after transcatheter aortic valve replacement in bicuspid vs tricuspid aortic valve stenosis. Abbreviations as in Figure 2.

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  Figure 5. Forest Plot for Major Bleeding in Transcatheter Aortic Valve Replacement for Bicuspid vs Tricuspid Aortic Valve Stenosis Forest plot comparing rates of major bleeding after transcatheter aortic valve replacement in bicuspid vs tricuspid aortic valve stenosis. Abbreviations as in Figure 2.

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  Figure 6. Forest Plot for 30-Day Stroke in Transcatheter Aortic Valve Replacement for Bicuspid vs Tricuspid Aortic Valve Stenosis Forest plot comparing 30-day stroke after transcatheter aortic valve replacement in bicuspid vs tricuspid aortic valve stenosis. Abbreviations as in Figure 2.

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  Figure 7. Forest Plot for 30-Day Mortality in Transcatheter Aortic Valve Replacement for Bicuspid vs Tricuspid Aortic Valve Stenosis Forest plot comparing 30-day mortality after transcatheter aortic valve replacement in bicuspid vs tricuspid aortic valve stenosis. Abbreviations as in Figure 2.

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  Figure 8. Forest Plot for 1-Year Stroke in Transcatheter Aortic Valve Replacement for Bicuspid Aortic Valve vs Tricuspid Aortic Valve Aortic Stenosis Forest plot comparing 1-year stroke after transcatheter aortic valve replacement in bicuspid vs tricuspid aortic valve stenosis. Abbreviations as in Figure 2.

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  Figure 9. Forest Plot for 1-Year Mortality in Transcatheter Aortic Valve Replacement for Bicuspid Aortic Valve vs Tricuspid Aortic Valve Aortic Stenosis Forest plot comparing 1-year mortality after transcatheter aortic valve replacement in bicuspid vs tricuspid aortic valve stenosis. Abbreviations as in Figure 2.

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  Figure 10. Meta-regression of Transcatheter Aortic Valve Replacement in Bicuspid vs Tricuspid Aortic Valve Stenosis Meta-regression evaluating the association between study-level covariates and outcomes of transcatheter aortic valve replacement in bicuspid vs tricuspid aortic valve stenosis: (A) 30-day mortality, (B) 1-year mortality, (C) 30-day stroke, and (D) 1-year stroke. BEV = balloon-expandable valve; SEV = self-expanding valve; STS = Society of Thoracic Surgeons; TAV = tricuspid aortic valve; other abbreviations as in Figure 2.

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  Figure 11. Subgroup Analysis for 1-Year Mortality by Study Year Subgroup analysis of 1-year mortality stratified by study year for transcatheter aortic valve replacement in bicuspid vs tricuspid aortic valve stenosis. Abbreviation as in Figure 2.

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  Figure 12. Forest Plot for Moderate or Greater Paravalvular Leak (≥ Moderate) in Transcatheter Aortic Valve Replacement vs Surgical Aortic Valve Replacement for Bicuspid Aortic Valve Stenosis Forest plot comparing moderate or greater paravalvular leak after transcatheter aortic valve replacement vs surgical aortic valve replacement in bicuspid aortic valve stenosis. TAVR = transcatheter aortic valve replacement; other abbreviations as in Figure 2.