Key result
Elevated HbA1c levels in patients undergoing cardiac surgery are associated with increased rates of wound infection, cardiovascular events, and renal failure, while mortality evidence is controversial.
Why the study?
Evidence remains controversial with no clear consensus on whether increased HbA1c levels are associated with increased perioperative mortality and morbidity following cardiac surgery.
Does elevated HbA1c affect mortality and morbidity in patients undergoing open heart surgery?
Does elevated HbA1c affect mortality and morbidity in patients undergoing open heart surgery?
Elevated HbA1c levels prior to cardiac surgery may predict higher postoperative morbidity, including wound infections and renal failure, highlighting the importance of preoperative glycemic control.
Answers are grounded in this paper and cite their sources.
May guide preoperative risk stratification in cardiac surgery; leaves open whether HbA1c optimization affects mortality.
There remains a significant paucity of information evaluating the effect of glycated HbA1c levels and its theorized effect on mortality and morbidity rates following cardiac surgery. Diabetes is a very common comorbidity in patients undergoing open heart surgery as there is shift in patient characteristics and being higher risk. Currently, the evidences are controversial and there is no clear consensus that increased HbA1c levels is associated with an increased perioperative mortality rate. However, reported literature are more commonly able to demonstrate elevated HbA1c levels to be associated with increased rates of wound infection, cardiovascular events and renal failure; thus, higher morbidities postoperatively. This literature review aims to examine the evidence synthesis behind each of morbidities and mortalities associated with open heart surgery and the impact of high HbA1c on the reported outcomes.
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Ansari et al. (2020) conducted a review in Cardiac surgery. Elevated HbA1c levels was evaluated on Mortality and morbidity rates. Elevated HbA1c levels in patients undergoing cardiac surgery are associated with increased rates of wound infection, cardiovascular events, and renal failure, while mortality evidence is controversial.
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