Key result
Acutely smoking one tobacco cigarette impaired flow-mediated dilation in smokers, whereas vaping a similar electronic cigarette dose did not.
Why the study?
Does acute use of tobacco cigarettes compared to electronic cigarettes impair flow-mediated dilation in healthy young people?
Observational
Does acute use of tobacco cigarettes compared to electronic cigarettes impair flow-mediated dilation in healthy young people?
Acute vaping of electronic cigarettes does not impair flow-mediated dilation unlike tobacco cigarettes, though long-term cardiovascular risks remain unknown.
Acute tobacco smoking impairs FMD unlike vaping; leaves open long-term cardiovascular risks of e-cigarettes.
In our study of otherwise healthy young people, baseline flow-mediated dilation (FMD), a predictor of atherosclerosis and increased cardiovascular risk, was not different among tobacco cigarette (TC) smokers or electronic cigarette (EC) vapers who had refrained from smoking, compared with nonsmokers. However, acutely smoking one TC impaired FMD in smokers, whereas vaping a similar EC "dose" (as estimated by change in plasma nicotine levels) did not. Finally, although it is reassuring that acute EC vaping did not acutely impair FMD, it would be premature and dangerous to conclude that ECs do not lead to atherosclerosis or increase cardiovascular risk.
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Haptonstall et al. (2020) conducted an observational in Healthy. Tobacco cigarettes and electronic cigarettes vs. Nonsmokers was evaluated on Flow-mediated dilation (FMD). Acutely smoking one tobacco cigarette impaired flow-mediated dilation in smokers, whereas vaping a similar electronic cigarette dose did not.