Key result
Intravenous pimobendan (0.15 mg/kg) and active rewarming successfully treated severe hypothermia (28.0°C) and pulsus alternans in an anaesthetised cat, with pulses equalising within 5 minutes.
Case Report (n=1)
Intravenous pimobendan may rapidly resolve pulsus alternans associated with severe hypothermia-induced myocardial dysfunction in felines.
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May support IV pimobendan for pulsus alternans in hypothermic cats; hypothesis-generating and needs prospective validation.
An 8‐year‐old, domestic, shorthair cat was presented for management of a significant degloving injury. After initial wound management, the cat was scheduled for anaesthesia to allow a free skin and pad graft to the affected foot. During anaesthesia, temperature rapidly dropped to a nidus of 28.0°C. Associated with this, the cat developed bradycardia and a marked pulsus alternans. The presumed ventricular myocardial dysfunction was treated with pimobendan (0.15 mg/kg intravenously). Within 5 minutes, the pulses equalised in amplitude. Additional active rewarming measures were initiated, which raised the temperature to 36.4°C before recovery in an incubator. A urinary catheter was placed to monitor for cold diuresis, and fluid therapy was altered to match urine output for 12 hours. A post‐anaesthetic echocardiogram revealed mild left ventricular concentric hypertrophy and dynamic right ventricular outflow tract obstruction indicating mild hypertrophic cardiomyopathy. The cat was discharged following 3 weeks of successful intensive wound and graft management.
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Matt McMillan (2023) conducted a case report in Severe hypothermia and pulsus alternans during anaesthesia (n=1). Pimobendan and active rewarming was evaluated on Resolution of pulsus alternans and hypothermia. Intravenous pimobendan (0.15 mg/kg) and active rewarming successfully treated severe hypothermia (28.0°C) and pulsus alternans in an anaesthetised cat, with pulses equalising within 5 minutes.
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