Key result
Over 13 years of follow-up, 3 of 4 cats in a family with asymptomatic hypertrophic cardiomyopathy died of aortic thromboembolism following progressive left atrial enlargement.
Case Report (n=4)
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This report documents the 13-year natural history of familial feline HCM, highlighting a progression from hyperdynamic to hypodynamic systolic function culminating in fatal aortic thromboembolism.
A feline domestic shorthair queen and her 3 offspring were all diagnosed with asymptomatic hypertrophic cardiomyopathy (HCM). The family has been followed for 13 years, and 3 cats have died of aortic thromboembolism (ATE). This communication documents the long-term progression of HCM in these cats that presented with mild left ventricular hypertrophy and hyperdynamic systolic ventricular function, developed progressive left atrial enlargement, and eventually resulted in hypodynamic left ventricular systolic function with relative left ventricular chamber dilation at the time of ATE.
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Baty et al. (2001) conducted a case report in Hypertrophic cardiomyopathy (HCM) (n=4). Hypertrophic cardiomyopathy was evaluated on Death from aortic thromboembolism (ATE). Over 13 years of follow-up, 3 of 4 cats in a family with asymptomatic hypertrophic cardiomyopathy died of aortic thromboembolism following progressive left atrial enlargement.
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